Dadih holds lactic acid microorganisms that are antimicrobial because it maybe appropriated to assert the well-being of fowl to a degree native chickens. This study aims to demonstrate the skill of dadih to restrain the progress of pathogenic microorganisms, that is to say Staphylococcus aureus, Escherichia coli and Poisoning caused by eating food. This study will likewise search for out invivo effect of dadih on the means privilege of native poultry contaminated accompanying Poisoning caused by eating food. Antimicrobial research uses plate spread system accompanying antimicrobial district limit. The invivo study was transported utilizing a entirely randomized design accompanying 4 situations and five replications place the limit was the growth of privilege means that is to say organ meat, bag fabrisius and hate. The results revealed that the antimicrobial test of dadih against Staphylococcus aureus, Escherichia coli and Poisoning caused by eating food made a district of restriction of 7.84, 6.63 and 8.34 mm. Dadih situation considerably distressed the portion of organ meat, bag fabrisius and hate. As end that dadih is smart to restrain the tumor of Staphylococcus aureus, Escherichia coli and Poisoning caused by eating food at medium substance accompanying a range of restriction district middle from two points 6.63-8.34. Dadih is likewise intelligent to claim the well-being of native hen.