This paper review mitigation strategies for farmer-herder conflict towards sustainable agriculture and food security in Nigeria. The relationship between farmers and herders deteriorates due to livestock-induced crop damage or other factors that may cause conflict particularly during the harvest season. At harvest, if care is not taken conflict becomes inevitable. And the consequences become severe as no party will be able to handle the outcome. A sound mediation and mitigation strategies that will stand the test of time is needed urgently to addressed the conflict so that it will not threatened national security and peaceful coexistence of the communities even though some of the disputes were straight forward, while others were intricate, requiring a viable possible approach to resolution. The mitigation strategies or approaches adopted in this paper includes; the establishment of open communication channel and peace building committee, ADR, symbiotic farm project, birth control, creation of awareness on climate change, revival of grazing reserve/land, and use of improved varieties. The paper concludes that there was the need for the involvement of all stakeholders to act and harnessed the problem of farmer-herder conflict in Nigeria so that prompt and sustainable agricultural production, food security and livelihoods could be achieved.